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Publications scientifiques de Darren E. Richard

Labbe A, Lafleur VN, Patten DA, Robitaille GA, Garand C, Lamalice L, Lebel M, Richard DE. The Werner syndrome gene product (WRN): a repressor of hypoxia-inducible factor-1 activity. Experimental cell research, 2012. 318: 1620-32

Avvakumov N, Lalonde ME, Saksouk N, Paquet E, Glass KC, Landry AJ, Doyon Y, Cayrou C, Robitaille GA, Richard DE, Yang XJ, Kutateladze TG, Cote J. Conserved Molecular Interactions within the HBO1 Acetyltransferase Complexes Regulate Cell Proliferation. Molecular and cellular biology, 2012. 32: 689-703

Lambert CM, Roy M, Robitaille GA, Richard DE, Bonnet S. HIF-1 inhibition decreases systemic vascular remodelling diseases by promoting apoptosis through a hexokinase 2-dependent mechanism. Cardiovascular research, 2010. 88: 196-204

Lambert CM, Roy M, Meloche J, Robitaille G, Agharazii M, Richard DE, Bonnet S. Tumor necrosis factor inhibitors as novel therapeutic tools for vascular remodeling diseases. American journal of physiology. Heart and circulatory physiology, 2010. 299: H995-1001

Patten DA, Lafleur VN, Robitaille GA, Chan DA, Giaccia AJ, Richard DE. Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species. Molecular biology of the cell, 2010. 21: 3247-57

Cellier E, Midaoui AE, Robitaille GA, Richard DE, Lariviere R, Lebel M. Effects of TGF-beta1 on endothelial factors. Archives of physiology and biochemistry, 2010. 116: 50-5

Michaud MD, Robitaille GA, Gratton JP, Richard DE. Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells. Arteriosclerosis, thrombosis, and vascular biology , 2009. 29: 902-8

Guo J, Chen H, Ho J, Mancini J, Sontag T, Laporte SA, Richard DE, Lebrun JJ. TGFbeta-induced GRK2 expression attenuates AngII-regulated vascular smooth muscle cell proliferation and migration. Cellular signalling, 2009. 21: 899-905

Lauzier MC, Robitaille GA, Chan DA, Giaccia AJ, Richard DE. (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors. Molecular pharmacology, 2008. 74: 282-8

Page EL, Chan DA, Giaccia AJ, Levine M, Richard DE. Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion. Molecular biology of the cell, 2008. 19: 86-94

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