René C-Gaudreault
- Formation
- à venir
Aucune offre active
Autres opportunités de carrière
- Axe principal
- Cancer
- Adresse
- 10, rue de l'Espinay, E0-171
Québec (Québec)
CANADA G1L 3L5 - Téléphone
- +1 418-525-4444, poste 52363
- Télécopieur
- +1 418-525-4372
- Courriel
- Rene.C-Gaudreault@crsfa.ulaval.ca
Publications récentes (voir toutes les publications de ce chercheur)
Fortin S, Bouchon B, Chambon C, Lacroix J, Moreau E, Chezal JM, Degoul F, C-Gaudreault R. Characterization of the Covalent Binding of N-Phenyl-N'-(2-chloroethyl)ureas to {beta}-Tubulin: Importance of Glu198 in Microtubule Stability. The Journal of pharmacology and experimental therapeutics,
2011. 336: 460-7
Fortin S, Wei L, Moreau E, Lacroix J, Cote MF, Petitclerc E, Kotra LP, C-Gaudreault R. Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4. Journal of medicinal chemistry,
2011. 54: 4559-80
Fortin S, Wei L, Moreau E, Lacroix J, Cote MF, Petitclerc E, Kotra LP, Gaudreault RC. Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships. European journal of medicinal chemistry,
2011. 46: 5327-42
Marceau F, Bawolak MT, Lodge R, Bouthillier J, Gagne-Henley A, C-Gaudreault R, Morissette G. Cation trapping by cellular acidic compartments: Beyond the concept of lysosomotropic drugs. Toxicology and applied pharmacology,
2011. Epub
Fortin S, Lacroix J, Cote MF, Moreau E, Petitclerc E, C-Gaudreault R. Quick and simple detection technique to assess the binding of antimicrotubule agents to the colchicine-binding site. Biological procedures online,
2010. 12: 113-7
Mounetou E, Miot-Noirault E, Gaudreault RC, Madelmont JC. N-4-iodophenyl-N'-2-chloroethylurea, a novel potential anticancer agent with colon-specific accumulation: radioiodination and comparative in vivo biodistribution profiles. Investigational new drugs,
2010. 28: 124-31
Fortin S, Moreau E, Lacroix J, Cote MF, Petitclerc E, C-Gaudreault R. Synthesis, antiproliferative activity evaluation and structure-activity relationships of novel aromatic urea and amide analogues of N-phenyl-N'-(2-chloroethyl)ureas. European journal of medicinal chemistry,
2010. 45: 2928-37
Patenaude A, Fortin JS, Deschenes R, Cote MF, Lacroix J, C-Gaudreault R, Petitclerc E. Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation. Canadian journal of physiology and pharmacology,
2010. 88: 1102-14
Fortin S, Wei L, Moreau E, Labrie P, Petitclerc E, Kotra LP, C-Gaudreault R. Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin. Bioorganic & medicinal chemistry,
2009. 17: 3690-7
Labbe JF, Cronier F, C-Gaudreault R, Auger M. Spectroscopic characterization of DMPC/DOTAP cationic liposomes and their interactions with DNA and drugs. Chemistry and physics of lipids,
2009. 158: 91-101
