Sheng-Xiang Lin
- Formation
- à venir
Aucune offre active
Autres opportunités de carrièreAucune étude clinique active
Autres études cliniques
- Axe principal
- Endocrinologie et génomique
- Adresse
- 2705, boulevard Laurier, T-4-50
Québec (Québec)
CANADA G1V 4G2 - Téléphone
- +1 418-525-4444, poste 42296
- Télécopieur
- +1 418-654-2761
- Courriel
- Sheng-Xiang.Lin@crchul.ulaval.ca
Publications récentes (voir toutes les publications de ce chercheur)
Martin M, Azzi A, Lin SX, Boivin G. Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity. Antiviral therapy,
2010. 15: 579-86
Aka JA, Mazumdar M, Chen CQ, Poirier D, Lin SX. 17beta-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Molecular endocrinology (Baltimore, Md.)
,
2010. 24: 832-45
Azzi A, Wang T, Zhu DW, Zou YS, Liu WY, Lin SX. Crystal structure of native cinnamomin isoform III and its comparison with other ribosome inactivating proteins. Proteins,
2009. 74: 250-5
Aka JA, Mazumdar M, Lin SX. Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: critical in the cell proliferation of breast cancer. Molecular and cellular endocrinology,
2009. 301: 183-90
Mazumdar M, Fournier D, Zhu DW, Cadot C, Poirier D, Lin SX. Binary and ternary crystal structure analyses of a novel inhibitor with 17beta-HSD type 1: a lead compound for breast cancer therapy. The Biochemical journal,
2009. Epub
Wang T, Zou YS, Zhu DW, Azzi A, Liu WY, Lin SX. Cinnamomin: separation, crystallization and preliminary X-ray diffraction study. Amino acids,
2008. 34: 239-43
Fournier D, Poirier D, Mazumdar M, Lin SX. Design and synthesis of bisubstrate inhibitors of type 1 17beta-hydroxysteroid dehydrogenase: Overview and perspectives. European journal of medicinal chemistry,
2008. 43: 2298-306
Lin YB, Zhu DW, Wang T, Song J, Zou YS, Zhang YL, Lin SX. An extensive study of protein phase diagram modification: increasing macromolecular crystallizability by temperature screening Crystal growth and design,
2008. 8: 4277-4283
Zhou M, Azzi A, Xia X, Wang ED, Lin SX. Crystallization and preliminary X-ray diffraction analysis of E. coli arginyl-tRNA synthetase in complex form with a tRNA(Arg). Amino acids,
2007. 32: 479-82
Qiu W, Zhou M, Mazumdar M, Azzi A, Ghanmi D, Luu-The V, Labrie F, Lin SX. Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase. The Journal of biological chemistry,
2007. 282: 8368-79
