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Frédéric Calon

Formation
B.Sc (biochimie)
B.Pharm (Pharmacie)
Ph.D.

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Principal area
Neuroscience
Address
2705, boulevard Laurier, T-2-50
Québec (Quebec)
CANADA G1V 4G2
Phone
+1 418-525-4444, extension 48697
Fax
+1 418-654-2298
Email
Frederic.Calon@crchul.ulaval.ca

Dr Frederic Calon is biochemist-pharmacist dedicated to the development of new treatment for neurodegenerative diseases, which affect more that 500,000 Canadians. Dr Calon and his collaborators have contributed to the discovery of a neuroprotective effect of omega-3 fatty acids in animal models of Alzheimer's and Parkinson’s disease. He has published over 75 papers, including in highly-cited journals in the field of neuroscience. His h-index has recently reached 31. Dr Calon was recruited at Université Laval in July 2003 where he gathered significant support from the Canadian Institutes of Health Research (CIHR), the Alzheimer Society Canada (ASC), the Parkinson Society Canada, the Canadian Foundation for Innovation and other organisms. Dr Calon’s research team currently comprises 1 postdoctoral fellow, 7 graduate students and 2 research professionals. The ultimate goal of his research is to accelerate the transfer of knowledge from basic neuroscience to clinical applications for brain diseases.

 

 

Research project(s) recognized by Université Laval (in French)

Other active research project(s)

No active project

Recent publications (see all publication from this researcher)

Rose C, Peoc'h K, Chasseigneaux S, Paquet C, Dumurgier J, Bourasset F, Calon F, Laplanche JL, Hugon J, Allinquant B. New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer's disease. BMC neuroscience,  2012. 13: 84
Arsenault D, Julien C, Calon F. Chronic dietary intake of alpha-linolenic acid does not replicate the effects of DHA on passive properties of entorhinal cortex neurons. The British journal of nutrition,  2012. 107: 1099-111
Bousquet M, St-Amour I, Vandal M, Julien P, Cicchetti F, Calon F. High-fat diet exacerbates MPTP-induced dopaminergic degeneration in mice. Neurobiology of disease,  2012. 45: 529-38
Paris-Robidas S, Brochu E, Sintes M, Emond V, Bousquet M, Vandal M, Pilote M, Tremblay C, Di Paolo T, Rajput AH, Rajput A, Calon F. Defective dentate nucleus GABA receptors in essential tremor. Brain : a journal of neurology,  2012. 135: 105-16
St-Amour I, Bousquet M, Pare I, Drouin-Ouellet J, Cicchetti F, Bazin R, Calon F. Impact of intravenous immunoglobulin on the dopaminergic system and immune response in the acute MPTP mouse model of Parkinson's disease. Journal of neuroinflammation,  2012. 9: 234
Do TM, Noel-Hudson MS, Ribes S, Besengez C, Smirnova M, Cisternino S, Buyse M, Calon F, Chimini G, Chacun H, Scherrmann JM, Farinotti R, Bourasset F. ABCG2- and ABCG4-Mediated Efflux of Amyloid-beta Peptide 1-40 at the Mouse Blood-Brain Barrier. Journal of Alzheimer's disease : JAD,  2012. 30: 155-66
Arsenault D, Julien C, Chen CT, Bazinet RP, Calon F. Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice. Journal of neurochemistry,  2012. Epub
Bories C, Guitton MJ, Julien C, Tremblay C, Vandal M, Msaid M, De Koninck Y, Calon F. Sex-dependent alterations in social behaviour and cortical synaptic activity coincide at different ages in a model of Alzheimer's disease. PLoS ONE,  2012. 7: e46111
Filali M, Lalonde R, Theriault P, Julien C, Calon F, Planel E. Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD). Behavioural brain research,  2012. 234: 334-42
Bousquet M, Calon F, Cicchetti F. Impact of omega-3 fatty acids in Parkinson's disease. Ageing research reviews,  2011. 10: 453-63
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